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Compound 5 induces apoptosis in Jurkat (upper panels) and A549 cells (bottom panels). Cells were cultured for 24 h in the presence of compound 5 (0.5 μM), alone or combined with the general caspase inhibitor z-VAD-fmk or left untreated (Control). Nuclei were stained with Hoechst 33342 (10 μg/mL), and cells were photographed under UV light. Magnification ×400.
