Table 1. Association of WNT5A rs524153 and rs504849 variants with CHM in all samples.
| SNPs | Genetic model | Pattern | Control | Case | P-value* |
MAF |
OR (95% CI) | ||
|---|---|---|---|---|---|---|---|---|---|
| Control | Case | Database# | |||||||
| rs524153 | Codominant | AA/AC/CC | 336/351/111 | 498/569/143 | 0.25 | 0.36 | 0.35 | 0.37 | NA |
| Dominant | AA/AC + CC | 336/462 | 498/712 | 0.69 | 1.04 (0.87–1.24) | ||||
| Recessive | AA + AC/CC | 687/111 | 1067/143 | 0.16 | 0.83 (0.63–1.08) | ||||
| rs504849 | Codominant | AA/AG/GG | 339/347/112 | 508/554/148 | 0.5 | 0.36 | 0.35 | 0.37 | NA |
| Dominant | AA/AG + GG | 339/459 | 508/702 | 0.75 | 1.03 (0.86–1.24) | ||||
| Recessive | AA + AG/GG | 686/112 | 1062/148 | 0.33 | 0.88 (0.67–1.14) | ||||
*Adjusted by sex; OR = odds ratio; CI = confidence interval; NA = not available.
#MAF = minor allele frequency from data of Han Chinese in the 1000 Genome Project.