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. Author manuscript; available in PMC: 2015 Nov 13.
Published in final edited form as: Cell. 2015 Aug 13;162(4):727–737. doi: 10.1016/j.cell.2015.07.019

Figure 2. Translocations in malaria GC B cells.

Figure 2

A- Schematic diagram of the protocol to identify genomic rearrangements induced by Plasmodium in vivo.

B- Chromosome distribution of rearrangement-associated reads captured by I-SceI breaks on chromosome 15.

C- Profile of rearrangements around the I-SceI site. Dotted lines represent AID deficient samples.

D- Proportion of genic rearrangements.

E- Frequency of rearrangements at genes with various levels of transcription. Empty bars represent AID deficient samples. Dashed line represents the expected frequency based on random model.

For all, rearrangements from malaria GC B cells are compared to cultured B cells (Klein et al., 2011). See also Figure S2.