Fig. 1.

Body weight, liver weight, and liver-to-body-weight ratio in male and female hPXR mice. Male and female hPXR mice were orally administered saline (control; □) or EtOH (4.5 g/kg; ▪) every 12 hours for a total of three doses and killed 4 hours after the final dose. Body weight (A), liver weight (B), and liver-to-body-weight ratios (C) were determined. Data represent the mean ± S.E.M. (n = 8–9). *P < 0.05 between male and female mice treated with saline (control); ^†P < 0.05 between male and female mice treated with EtOH.