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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Alcohol. 2015 Mar 6;49(3):237–243. doi: 10.1016/j.alcohol.2015.02.003

Figure 3. Ethanol withdrawal induces anxiety-like behavior in the elevated plus maze.

Figure 3

Mice were exposed to ethanol injections (A, B) or ethanol liquid diet (C, D). During withdrawal, mice were placed in the EPM for 10 min. The total time spent in the open arms (A, C) and the entry ratios (B, D) were significantly reduced during ethanol withdrawal. *p<0.05 compared to control-treated mice as measured by student t-test. N’s are 13, 9 for injections and 13, 13 for liquid diet.