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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Am J Surg Pathol. 2015 Sep;39(9):1226–1233. doi: 10.1097/PAS.0000000000000486

Table 1.

Evaluation of the association between specific histopathologic characteristics [fibromyxoid stroma (FMX) and infiltrative invasion] and outcomes of recurrence and lymph node metastasis. Adjusted odds ratio estimates were obtained using multivariable (MV) logistic regression models which, in addition to histopathology, included age, race and depth of invasion (DOI).

Unadjusted Estimates Adjusted Estimates
Model A1 Model B2
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
LN Metastasis

FMX 2.59 (1.06, 6.30) 0.0364 2.43 (0.98, 6.05) 0.1913 2.16 (0.85, 5.50) 0.1049
Infiltrative 1.52 (0.64, 3.60) 0.3441 1.38 (0.57, 3.37) 0.4761 1.14 (0.45, 2.90) 0.7809
Both3 1.99 (0.83, 4.77) 0.1235 1.83 (0.74, 4.57) 0.1924 1.58 (0.62, 4.05) 0.3418
Either4 2.03 (0.83, 5.01) 0.1222 1.89 (0.76, 4.73) 0.1726 1.61 (0.63, 4.15) 0.3199

Recurrence

FMX 2.25 (1.06, 4.77) 0.0348 2.16 (1.01, 4.61) 0.0470 1.95 (0.89, 4.24) 0.0935
Infiltrative 2.15 (1.01, 4.55) 0.0459 2.08 (0.94, 4.18) 0.0571 1.86 (0.85, 4.06) 0.1214
Both3 2.68 (1.25, 5.76) 0.0113 2.58 (1.19, 5.57) 0.0159 2.33 (1.06, 5.15) 0.0360
Either4 1.87 (0.84, 3.70) 0.1038 1.81 (0.85, 3.86) 0.1265 1.60 (0.73, 3.51) 0.2410
1

Estimates are adjusted for age and race.

2

Estimates are adjusted for age, race and DOI.

3

“Both” refers to samples having both FMX and Infiltrative characteristics versus those having only one or neither of the characteristics.

4

“Either” refers to samples having both or only one FMX or Infiltrative characteristics versus those having neither.