Fig. 5.

Attenuation of cytokine expression in cardiac allografts by anti-OX40L mAb treatment. Cardiac allografts in Rag-1^−/− B6 recipients were harvested on POD 100. Five tissues from each group were randomly selected for total RNA extraction. The intragraft expression of TNF-α, IFN-γ, TGF-β in the grafts in untreated versus anti-OX40L mAb-treated groups was analyzed by real-time RT-PCR. Data are presented as mean percentages (±SEM) that were statistically compared using Student's t-test test (*P <0.05 vs. untreated controls, n =5)