Table 3.
The age of SLE onset | Comorbidity | Immunoserology | Actual clinical status | Therapy | Arthritis psoriatica | Corticosteroids (mg PED) | SLICC |
---|---|---|---|---|---|---|---|
27 yrs | Lupus nephritis, autoimmune thyroiditis | ANA, aSSA, aSSB, aTPO | Relapsing, remission by MMF | Cyclophosphamide, mycophenolate mofetil, methylprednisolone | Peripheral | 25 | 1 |
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54 yrs | Hypertension, gout, ischaemic heart disease, COPD, cataract | ANA, a-dsDNA | Relapsing | Chloroquine, azathioprine, methylprednisolone, etanercept | Axial | 12.5 | 4 |
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45 yrs | — | ANA, a-SM, a-SSA | Remission | Oral methotrexate, leflunomide, chloroquine | — | — | 0 |
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24 yrs | Raynaud's syndrome, cutaneous vasculitis | ANA, a-dsDNA, a-SSA, aSSB, β2GPI IgG, hypocomplementaemia | Relapsing | Methylprednisolone, azathioprine, intravenous cyclophosphamide, IVIG, plasmapheresis, | — | 30 | 1 |
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33 yrs | Autoimmune thyroiditis, nephrotic syndrome | ANA, a-TPO, lupus anticoagulant, aCL IgM | Relapsing | Methylprednisolone, chloroquine, oral methotrexate, | — | 10 | 1 |
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57 yrs | Sjögren's syndrome | ANA, a-SSA, a-SSB, a-dsDNA, hypocomplementaemia | Relapsing | Oral methotrexate, methylprednisolone, sulfasalazine, intravenous cyclophosphamide | — | 20 | 1 |
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58 yrs | Sjögren's syndrome, urticaria vasculitis, ILD | ANA, a-dsDNA, a-chromatin, hypocomplementaemia | Worsening of ILD, psoriasis, immunoserology | Oral methotrexate, sulfasalazine, intravenous cyclophosphamide | Axial | 30 | 1 |
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29 yrs | Sjögren's syndrome | ANA, a-dsDNA, a-SSA, a-SSB, anti-RNP, a-U1RNP, a-TG | Worsening of psychosis, thrombocytopenia | Methylprednisolone | — | 12.5 | 1 |
SLE: systemic lupus erythematosus, COPD: chronic obstructive pulmonary disease, ILD: interstitial lung disease, ANA: anti-nuclear antibody, ACPA: anti-citrullinated peptide antibody, a-SSA: anti-Sjögren's syndrome A antibody, a-SSB: anti-Sjögren's syndrome B antibody, anti-RNP: anti-ribonucleoprotein antibody, a-dsDNA: anti-double stranded deoxyribonucleic acid antibody, β2GPI IgG: beta 2 glycoprotein I IgG, aCL IgM: anti-cardiolipin antibody immunoglobulin M, aU1RNP: anti-U1 ribonucleoprotein antibody, a-TG: anti-thyroglobulin antibody, a-TPO: anti-thyreoid peroxidase antibody, MMF: mycophenolate mofetil, PED: prednisolone equivalent dose, and SLICC: systemic lupus international collaborating clinics.