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(A) A thermogram showing the glass transition temperatures of (a) PLGA polymer (32.7°C), PLGA loaded with (b) 20 mg (32.8°C), (c), 10 mg (15.2°C), and (d) 0 mg OP (5.8°C). (B) Cumulative release kinetics for PLGA blank, 10 mg and 20 mg OP loaded PLGA. All PLGA-OP samples exhibited a biphasic release profile.
Abbreviations: OP, oseltamivir phosphate; PLGA, poly (lactic-co-glycolic acid).
