Table 2.

In vitro antifungal screening results of the synthesized compounds against different fungal strains

	C. albicansa (RCMB 05036)		C. parapsilosisb (RCMB 05064)		A. nigerc (RCMB 02568)		T. rubrumd (RCMB 010162)		T. mentagrophytese (RCMB 010173)
	MIC (µg/mL)	IC50 (µg/mL)	MIC (µg/mL)	IC50 (µg/mL)	MIC (µg/mL)	IC50 (µg/mL)	MIC (µg/mL)	IC50 (µg/mL)	MIC (µg/mL)	IC50 (µg/mL)
I	125	>125	125	>125	125	>125	125	>125	125	>125
II	0.98	8.83	0.98	8.38	1.95	21.4	3.9	42.2	7.81	48.8
III	31.25	120	15.63	89.4	15.63	65	7.81	42.3	15.63	93.4
IV	3.9	34	3.9	32.6	15.63	68.2	7.81	45.5	7.81	52.7
V	0.98	7.01	0.98	7.59	0.98	7.25	3.9	31.6	3.9	41.6
VI	7.81	30.7	1.95	17	3.9	35.8	3.9	42.2	3.9	53.7
VII	0.98	7.91	1.95	18.3	1.95	16.6	3.9	33.3	3.9	43.9
Miconazole	1.95	20.2	1.95	16.5	3.9	33.9	7.81	36.4	7.81	38.1
Fluconazole	15.63	79	7.81	51	7.81	32.8	15.63	72.7	31.25	111
Amphotericin B	1.95	10.2	0.98	6.99	1.95	15	7.81	44.6	7.81	31.6

Notes:

^aCandida albicans;

^bCandida parapsilosis;

^cAspergillus niger;

^dTrichophyton rubrum;

^eTrichophyton mentagrophytes.

Abbreviations: MIC, minimum inhibitory concentration; IC₅₀, half maximal inhibitory concentration.