Table 3.

Anti-HLA Ab profiles of patients with collagen disease in the stable and AoDILD states.

	BEADS#	NC	STABLE	AODILD	P
Class I	003	0.0	231.7 (192.6)	164.6 (147.9)	0.0038
Class I	004	10.7	208.8 (208.0)	169.3 (174.6)	0.1578
Class I	005	23.8	211.4 (200.9)	170.2 (200.0)	0.1155
Class I	009	21.3	276.6 (244.6)	193.4 (173.8)	0.0066
Class I	011	54.4	272.1 (180.9)	207.2 (98.3)	0.0324
Class I	014	69.7	273.1 (263.7)	207.1 (232.3)	0.0214
Class I	016	24.1	230.4 (252.0)	183.5 (231.5)	0.0980
Class I	017	1.1	229.1 (273.0)	175.0 (239.4)	0.0422
Class I	046	33.0	228.5 (194.3)	172.2 (163.1)	0.0264
Class I	049	13.1	298.5 (409.5)	243.1 (383.6)	0.0422
Class I	077	13.5	192.2 (234.5)	152.2 (229.1)	0.0480
Class I	078	1.8	129.5 (123.5)	89.2 (71.7)	0.0230
Class II	050	0.0	160.3 (201.0)	113.7 (150.4)	0.0736
Class II	053	100.1	503.0 (709.8)	554.3 (848.1)	0.4118
Class II	056	18.2	314.5 (532.4)	317.7 (491.0)	0.2418
Class II	057	46.6	311.6 (388.3)	233.1 (290.3)	0.0653
Class II	059	5.0	233.9 (351.1)	250.8 (353.4)	0.5449
MICA	074	38.6	233.6 (173.3)	183.7 (169.5)	0.0980
MICA	075	12.7	198.3 (413.2)	252.5 (598.3)	0.0780
Average
Class I		22.2	231.8 (214.2)	177.2 (185.6)	0.0186
Class II		34.0	304.7 (405.2)	293.9 (412.6)	0.1658
MICA		25.7	215.9 (241.8)	218.1 (318.7)	0.1658

Notes: Average values of each group are shown. Standard deviations are shown in parenthesis. Differences were tested by Wilcoxon signed-rank test. Specific antigens coated on the fluorescence beads are described in Supplementary Table S1.

Abbreviations: HLA, human leukocyte antigen; AoDILD, acute-onset diffuse interstitial lung disease; NC, negative control; Ab, antibody.