Table 3.

Association between metabolic syndrome and systolic and diastolic echocardiography abnormalities in adult survivors of childhood cancer.

	3D Echo <50%		Abnormal global Longitudinal Strain		Abnormal Global Circumferential strain		Diastolic Grade 1-3		Abnormal Septal e’		Abnormal Left Atrial Volume
	RR	95% CI	RR	95% CI	RR	95% CI	RR	95% CI	RR	95% CI	RR	95% CI
Metabolic Syndrome
Yes	1.07	0.74 - 1.53	1.94	1.66 - 2.28	1.02	0.84 - 1.24	1.68	1.39 - 2.03	1.65	1.35 - 2.02	1.41	1.14 - 1.74
No	1		1		1		1		1		1
Abdominal Obesity
Yes	1.34	0.99 - 1.82	1.73	1.48 - 2.01	1.1	0.92 - 1.32	1.69	1.39 - 2.06	1.49	1.23 - 1.82	1.83	1.53 - 2.19
No	1		1		1		1		1		1
Triglycerides ≥150 mg/dl
Yes	1.01	0.70 - 1.44	1.65	1.40 - 1.95	1.01	0.82 - 1.23	1.44	1.17 - 1.78	1.35	1.07 - 1.70	1.03	0.79 - 1.33
No	1		1		1		1		1		1
Low HDL Cholesterol
Yes	1.01	0.74 - 1.38	1.4	1.23 - 1.59	0.92	0.78 - 1.08	1.36	1.14 - 1.62	1.20	0.97 - 1.47	1.20	0.98 - 1.47
No	1		1		1		1		1		1
Hypertension
Yes	1.44	1.22 - 1.70	1.48	1.33 - 1.65	1.04	0.92 - 1.18	1.39	1.22 - 1.58	1.34	1.17 - 1.55	1.30	1.13 - 1.49
No	1		1		1		1		1		1
Fasting Glucose ≥100 mg/dl
Yes	1.02	0.75 - 1.39	1.37	1.19 - 1.59	1.06	0.89 - 1.25	1.42	1.18 - 1.70	1.47	1.22 - 1.77	1.00	0.81 - 1.25
No	1		1		1		1		1		1

Adjusted for current age, age at diagnosis, race/ethnicity, sex, chest RT and anthracycline exposure