Fig. 1.
Prevalence trend for neural tube defects per 10,000 live-births in Costa Rica from 1987–1991; 1996–2012. Source: Registry Center for Congenital Anomalies (Centro de Registro de Enfermedades Congénitas—CREC). Note: *1992–1995 data were excluded from the analysis because there were only 8 hospitals participating in CREC. Dotted lines denote data from 8 hospitals participating in CREC