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. Author manuscript; available in PMC: 2015 Aug 17.
Published in final edited form as: Adv Funct Mater. 2014 Dec 17;25(7):1024–1034. doi: 10.1002/adfm.201402930

Figure 7.

Figure 7

IC and IV injections of MSCs improved functional recovery of brain, but did not attenuate infarct volume. A) A representative set of T2-weighted coronal brain MR images in ischemic rats after IC and IV MSC injection. White area indicates infarct area. B) Infarct volume after treatment in the four groups from (A). Functional recovery was evaluated using a Rotarod test (C), neurological scores (D), and elevated body swing test (E). Behavioral tests were performed at one day before MCAO and after 1- to 14-day cell transplantation. Data are mean ± SD, n = 8 per group. *, p < 0.05, **, p < 0.01, and ***, p < 0.001, IC-MSC versus IC-PBS; #, p < 0.05, and ###, p < 0.001, IV-MSC versus IV-PBS.