Table 1.
General characteristics of individuals grouped according to diagnoses.
| Variables | Controls (n = 50) | COPD (n = 50) | P value |
|---|---|---|---|
| Gender F/M (n) | 21/29 | 20/30 | 0.80 |
| Active smokers (%) | 61 | 43 | 0.53 |
| Pack/years | 35.0 (26.2–41.5) | 50.0 (30.0–60.0) | 0.01 |
| Age (years) | 48.5 ± 7.4 | 64.0 ± 8.8 | <0.001 |
| FEV1 (%) | 110.0 ± 15.7 | 49.8 ± 16.8 | <0.001 |
| FEV1/FVC (%) | 81.0 (77.0–84.0) | 48.0 (38.0–61.0) | <0.001 |
| 6 MWD (m) | 562.5 (497.9–624.0) | 411.0 (357.0–486.0) | <0.001 |
| BMI (kg/m2) | 24.4 (22.5–26.5) | 24.8 (22.3–27.6) | 0.41 |
| FFM (kg) | 47.0 (39.4–53.4) | 42.1 (37.3–45.6) | 0.01 |
| IFFM (kg/m2) | 17.4 (15.4–18.2) | 16.3 (14.8–17.5) | 0.06 |
Data are reported as the means ± SD or as the medians (interquartile range (25–75%)). F/M = female/male; FEV1 = forced expiratory volume in the first second (% of predicted); FVC = forced vital capacity (% of predicted); 6 MWD: six-minute walk distance; FFM: fat-free mass; IFFM: index fat-free mass. The P values refer to COPD compared with the control (unpaired t-test or Mann-Whitney test and chi-square).