Table 2.
Inflammatory markers in the serum of control subjects and COPD patients.
| Variables | Control (n = 50) | COPD (n = 50) | P value |
|---|---|---|---|
| TNF-α (pg/mL) | 3.9 (3.6–5.4) | 4.5 (4.1–5.1) | 0.05 |
| IL-6 (pg/mL) | 0.3 (0.2–0.6) | 1.1 (0.8–1.9) | <0.001 |
| IL-8 (pg/mL) | 4.9 (3.4–7.1) | 4.1 (3.3–7.2) | 0.48 |
| CRP (mg/L) | 1.1 (0.6–2.2) | 6.3 (2.7–9.3) | <0.001 |
| Neutrophils (cell/mm3) | 3605 (2900–4342) | 4712 (4037–5667) | <0.001 |
| Lymphocytes (cell/mm3) | 1750 (1529–2090) | 1720 (1470–2397) | 0.94 |
| Leukocytes (cell/mm3) | 6400 (5300–7300) | 7600 (7000–9125) | <0.001 |
Data are reported as the median (interquartile range (25–75%)). TNF-α: tumor necrosis factor; IL-6: interleukin-6; IL-8: interleukin-8; CRP: C-reactive protein. The P values refer to COPD compared with the control (Mann-Whitney test and chi-square).