Table 2.
Expression of selected immunity related genes in vaccinated animals.
| Genes | BCG | ΔbfrB | Immunity type | ||
|---|---|---|---|---|---|
| Mean* | SE | Mean* | SE | ||
| Il1a | 1.28 | 0.59 | 1.23 | 0.57 | Th1 |
| Il1b | −1.09 | 0.10 | −1.05 | 0.19 | Th1 |
| Il10 | 1.20 | 0.21 | 1.04 | 0.18 | Th2, Th17 |
| Il13 | 1.11 | 0.14 | 1.16 | 0.15 | Th2, Th17 |
| Il12a | −5.86 | 0.10 | −2.21 | 0.28 | Th1 |
| Il12b | 1.18 | 0.38 | 1.17 | 0.51 | Th1, Th17 |
| Il18ra | −1.04 | 0.18 | −1.19 | 0.26 | Th1 |
| Ccl2 | −1.09 | 0.11 | 1.13 | 0.07 | Th17 |
| Ccl7 | −8.65 | 0.10 | 1.22 | 0.64 | Th2, Th17 |
| Ccl8 | −4.12 | 0.17 | 5.34 | 4.82 | Th2 |
| Ccl12 | 1.81 | 1.04 | 4.78 | 3.64 | Th17 |
| Cxcl1 | −1.72 | 0.38 | 7.13 | 6.25 | Th17 |
| Cxcl3 | −1.27 | 0.37 | 4.92 | 3.40 | Th2 |
| Cxcl5 | 2.53 | 1.13 | 5.11 | 4.55 | Th17 |
| Cxcl11 | −1.03 | 0.12 | 1.01 | 0.08 | Th1 |
| Tnfa | 1.13 | 0.59 | −2.51 | 0.29 | Th1, Th17 |
| Tgfb | −1.35 | 0.36 | −1.27 | 0.41 | Th2 |
| Timp1 | 1.35 | 0.46 | 1.43 | 0.18 | Th1, Th17 |
| Il1r2 | −1.48 | 0.22 | −1.26 | 0.21 | Th2 |
| Nos2 | −2.36 | 0.13 | −1.03 | 0.39 | Th1 |
∗Values shown are average from eight data points (duplicates of 4 animals per group).