Table 2.
Genotypes and allele distribution of IL17A rs2275913 and IL17F rs763780 in the patients with chronic periodontitis and controls from Southern Brazil.
| Genotype | All subjects | Nonsmokers | ||||
|---|---|---|---|---|---|---|
| Patients | Controls | Patients | Controls | |||
|
N = 140 n (%) |
N = 173 n (%) |
N = 56 n (%) |
N = 127 n (%) |
|||
| rs2275913 | ||||||
| GG | 67 (47.9) | 87 (50.3) | Ref. | 25 (44.6) | 61 (48.0) | Ref. |
| AA | 18 (12.9) | 12 (7.0) | ∗ | 9 (16.1) | 10 (7.9) | |
| AG | 55 (39.2) | 74 (42.7) | 22 (39.3) | 56 (44.1) | ||
| AA/AG | 73 (52.1) | 86 (49.7) | 31 (55.4) | 66 (52.0) | ||
| GG/AG | 122 (87.1) | 99 (57.2) | 47 (83.9) | 117 (92.1) | ||
| Allele | ||||||
| A | 91 (32.5) | 98 (28.3) | 40 (35.7) | 76 (30.0) | ||
| G | 189 (67.5) | 248 (71.7) | 72 (64.3) | 178 (70.0) | ||
| rs763780 | ||||||
| TT | 125 (89.3) | 158 (91.3) | Ref. | 49 (87.5) | 116 (91.3) | Ref. |
| CC | 1 (0.7) | 0 | 1 (1.8) | 0 | ||
| TC | 14 (10.0) | 15 (8.7) | 6 (10.7) | 11 (8.7) | ||
| CC/TC | 15 (10.7) | 15 (8.7) | 7 (92.9) | 11 (8.7) | ||
| TT/TC | 139 (99.3) | 173 (100) | 55 (98.2) | 127 (100) | ||
| Allele | ||||||
| T | 264 (94.3) | 331 (95.7) | 104 (92.9) | 243 (95.7) | ||
| C | 16 (5.7) | 15 (4.3) | 8 (7.1) | 11 (4.3) | ||
∗Codominant model: P = 0.09; OR = 2.53; 95% CI = 1.07–5.99; recessive model: P = 0.03; OR = 2.46; 95% CI = 1.08–5.59.