Figure 4.
Regional association plot demonstrating the relationship between MAPT transcript expression levels (y-axis) and SNPs in LD with rs393152 on chromosome 17. The bottom panel indicates the location of genes in the region. Linkage Disequilibrium measured in the 1000 genomes European Populations using plink v1.07. As illustrated, SNPs in r2 LD =1 with rs393152 constituted the peak of the association signal with MAPT transcript expression levels.