Table 1.
Codes and molecular characteristics for alginates used in this study presented alongside levels of pepsin and trypsin inhibition. F(G) is the fraction of the alginate polymer composed of guluronate and F(M) the fraction of mannuronate. n(G > 1) is the number of consecutive guluronate residues above 1.
| F(G) | F(M) | F(GG) | F(MM) | F(MGM) | F(GGG) | n(G > 1) | Pepsin inhibition |
Trypsin inhibition |
|||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 mg/ml | 2.5 mg/ml | 1.25 mg/ml | 5 mg/ml | 2.5 mg/ml | 1.25 mg/ml | ||||||||
| FMC 2 | 0.66 | 0.34 | 0.54 | 0.23 | 0.076 | 0.51 | 15.47 | 26.00 ± 8.78 | 19.99 ± 7.46 | −3.07 ± 13.75 | 11.46 ± 6.54 | 2.74 ± 2.86 | 1.53 ± 3.02 |
| FMC 3 | 0.68 | 0.32 | 0.57 | 0.21 | 0.069 | 0.53 | 14.66 | 11.38 ± 10.63 | 3.95 ± 13.84 | −2.43 ± 8.87 | 4.39 ± 3.12 | 7.83 ± 1.48 | 5.88 ± 6.64 |
| FMC 4 | 0.51 | 0.49 | 0.34 | 0.32 | 0.124 | 0.3 | 8.97 | 25.46 ± 8.69 | 17.80 ± 6.19 | 10.96 ± 5.67 | 4.92 ± 6.55 | 7.68 ± 2.55 | 3.52 ± 6.13 |
| FMC 5 | 0.53 | 0.47 | 0.36 | 0.31 | 0.123 | 0.32 | 9.67 | 33.95 ± 5.25 | 25.20 ± 6.92 | 12.78 ± 8.99 | 10.44 ± 1.99 | 7.45 ± 2.59 | 7.87 ± 2.68 |
| FMC 6 | 0.52 | 0.48 | 0.35 | 0.31 | 0.122 | 0.3 | 8.15 | 19.23 ± 7.81 | 13.06 ± 9.93 | 1.91 ± 9.78 | 3.85 ± 3.41 | 8.25 ± 5.77 | 3.54 ± 3.87 |
| FMC 7 | 0.42 | 0.58 | 0.24 | 0.4 | 0.133 | 0.2 | 6.47 | 29.43 ± 5.44 | 16.89 ± 6.22 | 11.78 ± 6.48 | 7.29 ± 2.91 | 5.60 ± 0.79 | −1.67 ± 2.49 |
| FMC 9 | 0.45 | 0.55 | 0.26 | 0.36 | 0.136 | 0.2 | 5.78 | 42.57 ± 5.25 | 24.73 ± 8.84 | 14.54 ± 10.16 | −10.31 ± 10.99 | −10.02 ± 25.23 | −4.31 ± 12.13 |
| FMC 10 | 0.42 | 0.58 | 0.21 | 0.37 | 0.14 | 0.14 | 3.96 | 39.41 ± 6.71 | 13.38 ± 14.73 | 2.52 ± 11.24 | −1.70 ± 12.13 | 5.37 ± 5.24 | −1.13 ± 9.47 |
| FMC 12 | 0.35 | 0.65 | 0.19 | 0.49 | 0.111 | 0.13 | 4.54 | 38.13 ± 4.52 | 20.59 ± 10.28 | 11.79 ± 6.57 | −2.83 ± 11.61 | 0.35 ± 9.64 | 4.97 ± 17.73 |
| FMC 13 | 0.34 | 0.66 | 0.17 | 0.49 | 0.124 | 0.12 | 4.63 | 45.99 ± 5.97 | 31.42 ± 10.03 | 13.63 ± 4.92 | 4.23 ± 8.16 | 2.59 ± 13.33 | 2.72 ± 11.59 |
| LF120 | 0.424 | 0.576 | 0.24 | 0.391 | 0.156 | 0.183 | 4.7 | 44.73 ± 10.98 | 28.46 ± 10.68 | 1.21 ± 7.74 | 6.22 ± 7.71 | 3.79 ± 10.77 | 3.50 ± 6.66 |
| LFR560 | 0.633 | 0.367 | 0.505 | 0.239 | 0.096 | 0.45 | 9.9 | 32.42 ± 5.31 | 18.34 ± 6.49 | 9.94 ± 7.85 | −6.76 ± 11.41 | 0.77 ± 10.58 | 0.25 ± 8.08 |
| LF10L | 0.45 | 0.553 | 0.257 | 0.362 | 0.153 | 0.19 | 4.4 | 42.66 ± 6.23 | 22.84 ± 5.84 | 8.18 ± 7.93 | −5.86 ± 8.66 | −4.38 ± 7.84 | −9.05 ± 6.65 |
| H120L | 0.45 | 0.551 | 0.276 | 0.379 | 0.15 | 0.22 | 5.9 | 46.09 ± 9.53 | 24.37 ± 11.90 | 9.81 ± 6.54 | 3.07 ± 5.70 | 4.66 ± 2.60 | 2.53 ± 5.56 |
| SF120 | 0.664 | 0.336 | 0.545 | 0.218 | 0.083 | 0.484 | 9.6 | 21.93 ± 5.42 | 8.83 ± 5.56 | 0.45 ± 5.31 | −7.20 ± 7.96 | 2.23 ± 4.00 | 10.05 ± 5.19 |
| SF200 | 0.68 | 0.322 | 0.573 | 0.218 | 0.079 | 0.537 | 16.7 | 13.10 ± 6.03 | 15.93 ± 6.37 | 14.11 ± 13.58 | −0.89 ± 2.46 | −1.35 ± 3.10 | −5.52 ± 2.53 |
| SF/LF | 0.66 | 0.336 | 0.548 | 0.22 | 0.081 | 0.506 | 13.8 | 15.56 ± 5.40 | 4.08 ± 6.86 | −5.26 ± 6.79 | 0.90 ± 7.99 | −2.88 ± 10.97 | −1.73 ± 2.90 |
| SF60L | 0.411 | 0.589 | 0.219 | 0.393 | 0.155 | 0.133 | 3.3 | 43.87 ± 7.36 | 15.50 ± 8.88 | 4.12 ± 11.67 | −2.11 ± 14.83 | −2.05 ± 17.15 | −9.14 ± 23.66 |