FIG 5.
Rescue of eye development by ELAV/Hu family RBPs in elav mutant eyes. (A) Schematic of the eFVGU elav rescue construct. FRT-mediated recombination results in loss of elav and GAL4 expression under the elav promoter. (B to D) Eye and eye discs of elave5 eFVGU; eyflp males. Neurons shown in panels C and D were stained with anti-ELAV and MAb 24B10, respectively. (E to J) Eyes of wild-type and elave5 eFVGU; eyflp males expressing ELAV/Hu family RBPs or Sxl from UAS transgenes. (K) Quantification of the eye size shown in panels B and E to J. Statistically significant rescue compared to results in the absence of a UAS transgene is indicated (***, P < 0.001).