TABLE 4.

Functional analysis of selected genes regulated by FOSL1

Molecule(s) in network	Score	Top disease(s) and/or function(s)
ADM, AKAP12, BCAR3, Cgm4, CSRP1, CYP11A1, DIO3, DUSP14, FDXR, FOSL1, IGFBP3, IL1R2, LY6E, MMD, MMP9, MT1, NOV, SEMA6D, TXNIP	41	Cardiovascular system development/function, organ morphology, organismal development
CHDH, CHSY1, DENND2C, EIF4E3, FLYWCH2, GNPTAB, HECA, MOSPD1, MYO1F, PARVG, PHLDB2, PPAP2A, RASL10B, RDH12, RILPL1, SALL1, TSPAN33	26	Cellular compromise, cell-to-cell signaling and interaction, cellular movement
CD47, GNE, HSPB1, HSPB8, IGDCC3, KRT15, NEDD4L, PBX3, Prl3d1, PTPRK, RDM1, ZAK, ZFP36L2	26	Hereditary disorder, neurological disease, organismal injury and abnormalities
ARHGDIB, CEACAM1, CLDN4, CRISPLD2, F3, ICAM2, LAMC2, PDGFA, PLSCR1, PPAP2B, STIM1, TIMP3	26	Cellular movement, cancer, tumor morphology
CLDN4, CPEB2, FAM110B, FDXR, FOSL1, FXYD6, GRHL1, HNF4A, ITIH3, RBKS, ROBO3, TIMP3	14	Cellular movement, cellular development, reproductive system development and function
CHCHD10	2	Cancer, cell cycle, cell death and survival
MLLT3	2	Cancer, cardiovascular disease, cardiovascular system development and function