Table 2.
Prognosis factors in univariate analysis.
| Variable | Overall survival | ||||
|---|---|---|---|---|---|
| β | HR | 95% CI | P value | ||
| BDNF | 0.005 | 1.005 | 1.000 | 1.009 | 0.034 |
| HVEM/TNFRSF14 | −0.079 | 0.924 | 0.858 | 0.996 | 0.038 |
| IL-24 | 0.040 | 1.041 | 1.006 | 1.078 | 0.023 |
| IL-29 | 0.012 | 1.012 | 1.002 | 1.023 | 0.021 |
| Leptin R | 0.008 | 1.008 | 1.001 | 1.015 | 0.018 |
| LRP-6 | 0.027 | 1.027 | 1.004 | 1.051 | 0.022 |
| ROBO4 | 0.002 | 1.002 | 1.000 | 1.004 | 0.045 |
| Age | 0.086 | 1.089 | 1.008 | 1.177 | 0.030 |
| Clinical response | 2.064 | 8.706 | 1.057 | 71.692 | 0.013 |
|
| |||||
| Cytokines | Overall model fit (P = 0.0023) | ||||
| β | HR | 95% CI | P value | ||
|
| |||||
| IL-24 (1) | 0.042 | 1.042 | 1.003 | 1.023 | 0.026 |
| IL-29 (2) | 0.014 | 1.014 | 1.005 | 1.081 | 0.017 |
β: coefficient provided by the Cox's regression model for a particular patient and cytokine; HR: hazard ratio (represents the factor by which the hazard changes for each one-unit increase of the cytokine expression); 95% CI: upper and lower limits of the confidence interval with a significance level of 0.05.