Table 3.
Prognosis factors in multivariate analysis.
| Cytokines | Overall survival | Overall model fit | ||||
|---|---|---|---|---|---|---|
| β | HR | 95% CI | P value | P value | ||
| IL-29 | 0.081 | 1.084 | 1.010 | 1.164 | 0.026 | 0.004212 |
| B7-1/CD80 | 4.351 | 77.574 | 1.138 | 5289.45 | 0.043 | 0.002494 |
| PD-ECGF | 0.264 | 1.302 | 0.944 | 1.797 | 0.108 | 0.001350 |
| EG-VEGF/PK1 | 0.003 | 1.003 | 1.000 | 1.005 | 0.049 | 0.000134 |
| NRG1-beta1/HRG1-beta1 | 0.020 | 1.020 | 0.994 | 1.047 | 0.129 | 0.000286 |
|
| ||||||
| Cytokines | Overall survival in the univariate analysis | |||||
| β | HR | 95% CI | P value | |||
|
| ||||||
| IL-29 | 0.012 | 1.012 | 1.002 | 1.023 | 0.021 | |
| B7-1/CD80 | 0.373 | 1.452 | 0.876 | 2.407 | 0.148 | |
| PD-ECGF | 0.044 | 1.045 | 0.997 | 1.096 | 0.068 | |
| EG-VEGF/PK1 | −0.0001 | 1.000 | 0.999 | 1.000 | 0.640 | |
| NRG1-beta1/HRG1-beta1 | −0.004 | 0.996 | 0.979 | 1.014 | 0.673 | |
β: coefficient provided by the Cox's regression model for a particular patient and cytokine; HR: hazard ratio (represents the factor by which the hazard changes for each one-unit increase of the cytokine expression); 95% CI: upper and lower limits of the confidence interval with a significance level of 0.05.