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. 2015 Aug 4;2015:102021. doi: 10.1155/2015/102021

Figure 1.

Figure 1

HQT ameliorates TNBS-induced colitis in a dose-dependent manner. Various doses of Huangqin-Tang decoction (HQT) (30–120 mg/kg) were administered following the 2,4,6-trinitrobenzenesulfonic acid (TNBS) enema and on the next 2 days. (a) Body weight changes (percentage of original body weight), (b) bleeding score, and (c) diarrhoea score were scored daily. (d) Rats were sacrificed on day 7 to measure colon length. (e) Myeloperoxidase (MPO) activity was assessed in colon homogenates as described in Section 2. (f) The production of tumor necrosis factor-α (TNF-α) in the colon was determined by enzyme-linked immunosorbent assay (ELISA). Results represent the mean ± SD from eight mice per group. * P < 0.05, ** P < 0.001 versus the control group. Δ P < 0.05, ΔΔ P < 0.001 versus TNBS-treated rats.