Table 1.

Ovid medline search strategy: Ovid MEDLINE^®, Ovid MEDLINE^® In-Process and Other Non-Indexed Citations, Ovid MEDLINE^®, Daily and Ovid OLDMEDLINE^®

No.	Search syntax
1	“Adolescent idiopathic scoliosis”.ab,ti.
2	(AIS and scoliosis).ab,ti.
3	Scoliosis/ and (exp adolescent/ or exp child/)
4	Or/1-3
5	“Curve progression”.ab,ti.
6	“Disease susceptibility”.ab,ti.
7	Prediction.ab,ti.
8	“Disease progression”.ab,ti.
9	Exp disease progression/
10	Disease susceptibility/
11	“Predictive value of tests”/
12	Exp decision support techniques/
13	Or/5-12
14	Scoliosis/ra
15	(Ogilvie JW or Ward K*).au. and scoliosis.ab,ti.
16	“Scoliscore”.mp.
17	“Axial biotech”.mp.
18	Moreau A*.au. and scoliosis.ab,ti.
19	4 and 13
20	13 and 14
21	Or/15-20
22	(genetic adj2 test*).ab,ti.
23	“Genetic predisposition”.ab,ti.
24	“Single nucleotide polymorphism”.ab,ti. Or (SNP and polymorphism).ab,ti.
25	Genetic Testing/
26	Exp genetic predisposition to disease/
27	Polymorphism, single nucleotide/
28	Or/22-27
29	4 and 28
30	30. 21 or 29