Table 4.

Results for activity of daily living and quality of life.

	Baseline		6 months		p-Value 6 months vs. baseline
	Mean	SD	Mean	SD
A
UHDRS functional capacity	12.0	8.7	12.7	9.7	0.465
UHDRS functional assessment	5.2	3.9	6.7	5.5	0.237
UHDRS behavioral assessment	8.0	4.6	4.2	5.3	0.057
HD-ADL	28.6a	11.0a	21.2a	16.6a	0.227
BFMDRS disability scale	14.2	7.8	13.0	8.9	0.302
SF-36 physical functioning	30.83	29.9	38.3	40.6	0.620
SF-36 physical role function	54.2	40.1	58.3	51.6	0.793
SF-36 bodily pain	66.7	51.6	81.7	40.2	0.648
SF-36 general health perception	63.0	21.5	79.2	12.7	0.169
SF-36 vitality	48.3	12.1	70.8	23.1	0.030#
SF-36 social role functioning	52.2	25.5	77.3	30.8	0.090
SF-36 emotional role functioning	72.2	44.4	77.8	40.4	0.788
SF-36 mental health	69.3	13.3	90.7	13.3	0.022##
B
UHDRS functional capacity	16.0	7.4	17.5	7.8	0.215
UHDRS functional assessment	6.5	4.0	9.2	4.9	0.102
UHDRS behavioral assessment	8.5	4.8	5.5	6.1	0.245
HD-ADL	25.3	6.7	10.7	7.0	0.080
BFMDRS disability scale	10.2	4.7	7.7	3.9	0.030#
SF-36 physical functioning	42.5	30.1	57.5	35.7	0.525
SF-36 physical role function	56.2	51.5	75.0	54.0	0.319
SF-36 bodily pain	50.0	57.7	75.0	50.0	0.638
SF-36 general health perception	68.5	7.0	76.5	15.4	0.380
SF-36 vitality	47.5	13.2	66.2	28.1	0.141
SF-36 social role functioning	56.2	31.4	66.0	32.7	0.430
SF-36 emotional role functioning	58.2	50.0	75.0	50.0	0.602
SF-36 mental health	61.0	3.8	87.0	15.4	0.063

^aData from five patients.

A: complete group (n = 6), B: chorea subgroup, Westphal patients excluded (n = 4).

SF-36, UHDRS functional capacity, functional assessment: increase = improvement.

BFMDRS disability scale, HD-ADL, UHDRS behavioral assessment, care giver rating: decrease = improvement.

Effect size (Cohen’s d): ^#1.22, ^##1.609.