Table 4.

Association of rs1051730 allele T with Lung Cancer and PAD

	Controls		Cases
Study Group	n	freq	n	freq	OR	(95% CI)	P
Lung Cancer
Iceland	28,752	0.342	665	0.398	1.27	(1.13 - 1.43)	4.1 × 10−5
Spain	1,474	0.390	269	0.483	1.46	(1.22 - 1.76)	5.4 × 10−5
The Netherlands	2,018	0.314	90	0.350	1.18	(0.86 - 1.61)	0.31
Foreign combined	3,492	-	359	-	1.38	(1.18 - 1.62)	6.6 × 10−5
All combined	32,244	-	1,024	-	1.31	(1.19 - 1.44)	1.5 × 10−8
PAD
Iceland	28,752	0.342	1,503	0.379	1.18	(1.09 - 1.27)	5.3 × 10−5
New Zealand	435	0.274	441	0.337	1.35	(1.10 - 1.65)	0.0041
Austria	403	0.352	457	0.395	1.20	(0.99 - 1.46)	0.068
Sweden	140	0.304	172	0.331	1.14	(0.81 - 1.60)	0.46
Italy	234	0.378	165	0.412	1.15	(0.86 - 1.54)	0.33
Foreign combined	1,212	-	1,235	-	1.23	(1.09 - 1.39)	5.9 × 10−4
All combined	29,964	-	2,738	-	1.19	(1.12 - 1.27)	1.4 × 10−7