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. 2015 Aug 18;16:144. doi: 10.1186/s12882-015-0138-x

Table 3.

Comparison of baseline characteristics among ESA responders, acute hyporesponders, and chronic hyporesponders: categorical variables

Chronic hyporesponders (n = 3086) Acute hyporesponders (n = 6632) ESA responders (n = 81,504) p-value
N % N % N %
Gender female 1633 52.9 3395 51.2 44,700 54.8 <0.0001
Race/ethnicity <0.0001
 American Indian 25 0.8 68 1.0 1153 1.4
 Asian 94 3.1 237 3.6 3063 3.8
 Black 1339 43.4 2806 42.3 30,309 37.2
 Hispanic 342 11.1 961 14.5 15,162 18.6
 Pacific Islander 25 0.8 49 0.7 708 0.9
 Other 204 6.6 432 6.5 4222 5.2
 White 1057 34.3 2079 31.4 26,887 33.0
Primary cause renal disease <0.0001
 Diabetes 1182 38.0 2769 41.8 35,969 44.1
 Hypertension 901 29.2 1981 29.9 24,936 30.6
Vascular access <0.0001
 Fistula 1726 55.9 3732 56.3 53,200 65.3
 Catheter 671 21.7 1579 23.8 11,382 14.0
 Graft 685 22.2 1321 19.9 16,904 20.7
Other 4 0.1 0 0 17 0.02
 Diabetes 1558 50.5 3389 51.1 43,279 53.1 0.0001
 Hypertension 1114 36.1 2401 36.2 28,282 34.7 0.0174
 Cardiac arrest 3 0.1 7 0.1 82 0.1 0.9929
 Myocardial infarction 9 0.3 13 0.2 163 0.2 0.1776
 COPD 160 5.2 298 4.5 3097 3.8 <0.0001
 History of GI bleed 68 2.2 73 1.1 815 1.0 <0.0001
 Liver disease 71 2.3 126 1.9 1304 1.6 0.0009
 HIV/AIDS 28 0.9 53 0.8 326 0.4 <0.0001
 Hepatitis B 22 0.7 27 0.4 245 0.3 <0.0001
 Septicemia 241 7.8 484 7.3 4646 5.7 <0.0001
 Pneumonia 108 3.5 206 3.1 1875 2.3 <0.0001
 Anemia hemolytic/sickle cell 68 2.2 33 0.5 245 0.3 <0.0001
 Myelodysplastic syndrome 40 1.3 27 0.4 82 0.1 <0.0001
 Monoclonal gammopathy 22 0.7 33 0.5 326 0.4 0.0006

COPD chronic obstructive pulmonary disorder, ESA erythropoietin-stimulating agent, GI gastrointestinal, HIV/AIDS Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome

P-values represent a chi square test