Table 1.
Inhibition concentration (μg/ml) of the saponin extract on 50 % bacterial growth and biofilm formation of Escherichia coli and Staphylococcus aureus
| Groups | E. coli | S. aureus | ||
|---|---|---|---|---|
| Growth | Biofilm | Growth | Biofilm | |
| Amo | 72.6 ± 7.9 | 72.8 ± 9.6 | 138.6 ± 11.0 | 129.8 ± 10.5 |
| Sap | 50.2 ± 5.7a | 43.6 ± 4.2a | 79.6 ± 9.1a | 70.2 ± 10.2a |
| Sap : Amo (1:1) | 30.4 ± 6.5a,b | 22.8 ± 5.2a,b | 59.0 ± 9.6a,b | 52.4 ± 8.0a,b |
| Sap : Amo (5:1) | 23.4 ± 5.6a,b | 18.6 ± 5.7a,b | 43.2 ± 5.9a,b | 39.2 ± 3.5a,b |
| Sap : Amo (10:1) | 21.6 ± 5.1a,b | 15.6 ± 3.5a,b | 35.2 ± 4.5a,b | 30.2 ± 7.0a,b |
| Ery | 69.2 ± 6.3 | 65.6 ± 10.5 | 126.2 ± 6.7 | 122.8 ± 8.3 |
| Sap : Ery (1:1) | 28.2 ± 5.2b,c | 26.8 ± 6.8b,c | 51.6 ± 8.0b,c | 44.4 ± 6.1b,c |
| Sap : Ery (5:1) | 24.4 ± 4.7b,c | 19.2 ± 4.8b,c | 35.4 ± 5.3b,c | 28.6 ± 6.3b,c |
| Sap : Ery (10:1) | 13.4 ± 3.9b,c | 12.8 ± 5.1b,c | 27.6 ± 5.7b,c | 22.8 ± 6.2b,c |
Data were presented as mean ± standard deviation (n = 5)
Amo amoxicillin, Sap saponin, Ery erythromycin
a p < 0.01, compared with amoxicillin
b p < 0.01, compared with the saponin
c p < 0.01, compared with erythromycin