Fig. 6.

Distribution of L1 elements on 3D models of the Xa and Xi. a 3D models of the Xa and Xi at 1 Mb resolution in mouse F1 brain colored to display the density of L1 elements (red indicates more L1 elements). L1 elements tend to be located at the inside of the Xi 3D structure. b Box plots for the Xa (left) and the Xi (right) showing L1 density at 1 Mb resolution grouped by the corresponding distances of the 1 Mb regions to the Xa chromosomal center or to the Xi superdomain centers, and empirical cumulative curves of 1 Mb regions binned based on their distance to the Xa chromosomal center or to the Xi superdomain centers for the L1-rich (red line, top 25 %) and L1-poor regions (blue line, bottom 25 %). The empirical cumulative density as a function of the distance to the chromosome or superdomain centers for the feature-rich and feature-poor regions were compared using one-side Wilcoxon rank-sum test