Table 4.

Vitamin D correlation, in vivo and intervention studies testosterone

Author	Reference #	Population	Subjects/specimens	Type of study	Intervention	Duration	Results
Wehr et al. 2010	[53]	Elderly	2,299Caucasian Male Subjects (age S2 ± 11)	Cross-sectional	-	-	Positive correlation seen between 25(OH)D levels and Testosterone and Androgen Levels
Pilz, Frisch & Koertke 2011	[59]	Healthy Males	54 Healthy Overweight Males (age range 20–49)	Intervention - RCT	3332 lU/Day of Vitamin Dor Placebo	12 Months	Significant ↑ in 25(0H)D, Total Testosterone, Bioactive Testosterone and Free Testosterone Positive relationship between higher
Kinuta et al. 2014	[60]	Rat Model	VDR Knockout Mice	Intervention - In Vivo	VDR Knockout Mice - Disruption of VDR gene	-	25(OH)D levels and inhibition of gonadal armoatization of testosterone