Table 4.
Frequency of Adverse Events in the Week Following Vaccination, by Study Group
| Adverse Event | Group 1, 40% ID (n = 65) | Group 2, 20% ID (n = 63) | Group 3, 100% IM (n = 64) | Group 4, 40% IM (n = 32) |
|---|---|---|---|---|
| Anya | 51 (33) | 46 (29) | 28 (18) | 31 (10) |
| Fever | 0 (0) | 3 (2) | 0 (0) | 3 (1) |
| Rash | 2 (1) | 2 (1) | 6 (4) | 6 (2) |
| Redness at injection siteb | 29 (19) | 35 (22) | 6 (4) | 9 (3) |
| Swelling at injection site | 8 (5) | 11 (7) | 5 (3) | 6 (2) |
| Tenderness at injection site | 15 (10) | 13 (8) | 17 (11) | 16 (5) |
| Itching at injection sitec | 11 (7) | 6 (4) | 0 (0) | 0 (0) |
Data are (%) (no.) of subjects. Differences were not statistically significant, unless otherwise indicated.
Abbreviations: ID, intradermal; IM, intramuscular.
a P = .008 for group 1 vs group 3, and P = .04 for group 2 vs group 3.
b P = .0007 for group 1 vs group 3, P ≤ .0001 for group 2 vs group 3, P = .03 for group 1 vs group 4, and P = .008 for group 2 vs group 4.
c P = .007 for group 1 vs group 3, and P = .04 for group 2 vs group 3.