Table 2. Percent of directed motion of pericentric chromatin.
| Minimum displacement | Untreated (n = 22 foci) | Benomyl (n = 16 foci) | kMT dynamics from mitotic simulationa | |||
|---|---|---|---|---|---|---|
| Parallel | Perpendicular | Parallel | Perpendicular | |||
| nm | ||||||
| 300 | 19% | 4% | 0% | 0% | 20% | |
| 350 | 16% | 1% | 0% | 0% | 14% | |
| 400 | 11% | 0% | 0% | 0% | 9% | |
a
Simulated kMT dynamics were generated using the default settings of a MATLAB Mitotic Spindle Simulation that incorporates kMT dynamics with a chromatin spring to recapitulate lacO fluctuation and stretching in WT and mutant cells (Stephens et al., 2013).