Table 1.
Effects on aggression/rejection behavior of female mice during mating task (mean ± sem).
Condition | Brain infusion condition | |||
---|---|---|---|---|
Veh | mPRα AS-ODN | mPRβ AS-ODN | mPRαβ AS-ODN | |
Experiment 1: effects of AS-ODNs to the lateral ventricle of ovx, E2 + P4-primed C57/BL6 mice | ||||
Aggression Quotient | 57 ± 7 | 80* ± 9 | 98* ± 2 | 87* ± 7 |
Experiment 2: effects of AS-ODNs to the VTA of ovx, E2 + P4-primed C57/BL6 mice | ||||
Aggression Quotient | 57 ± 7 | 80* ± 9 | 98* ± 2 | 87* ± 7 |
Experiment 3: effects of AS-ODNs to the VTA of ovx, E2 + P4-primed C57/BL6X129 mice | ||||
Aggression Quotient | 72 ± 7 | 79 ± 8 | 94 ± 4 | 89 ± 6 |
Experiment 4: effects of AS-ODNs to the VTA of ovx, E2 + P4-primed PRKO mice | ||||
Aggression Quotient | 78 ± 7 | 89 ± 5 | 92 ± 4 | 78 ± 8 |
indicates significant effect of AS-ODN to alter behavior compared to vehicle control (p < 0.05).