Table 4.
Local Peaks of Significant Clusters Showing Reduced Gray Matter in the Treatment-Resistant Patients Compared with the First-Line Antipsychotic Responders.
| Cortical region | Side | Cluster size | MNI peak coordinates (mm) | Local maximum p value* |
|---|---|---|---|---|
| Inferior temporal gyrus | Right | 1685 | 58 -56 -24 | 0.001 |
| Post-central gyrus | Bilateral | 1193 | -2 -46 72 | 0.006 |
| Middle frontal gyrus | Left | 797 | -36 2 48 | 0.007 |
| Anterior supramarginal gyrus | Right | 656 | 66 -24 26 | 0.010 |
| Superior frontal gyrus | Bilateral | 625 | 0 14 62 | 0.006 |
| Superior temporal gyrus (temporal pole) | Right | 175 | 60 10 -10 | 0.036 |
| Lateral occipital cortex | Right | 74 | 14 -70 50 | 0.028 |
| Supplementary motor cortex | Left | 35 | -12 2 38 | 0.039 |
*With family-wise error correction for multiple comparisons across space. p < 0.05 and >20 voxels.