Table 3.
AlloHSCT Z-Scores According to Disease and Treatment Characteristics
Z-Score | Height | Trabecular vBMD | Section Modulus | Periosteal Circumference | Endosteal Circumference | Muscle Cross-Sectional Area | Fat Cross-Sectional Area |
---|---|---|---|---|---|---|---|
TBI | |||||||
Yes | −1.38 ± 1.00 | −1.30 ± 1.40 | −0.95 ± 2.02 | −0.73 ± 1.26 | −0.16 ± 1.11 | −1.34 ± 1.42 | 0.79 ± 1.19 |
No | −0.40 ± 1.29 | −0.49 ± 0.88 | −0.09 ± 0.88 | −0.16 ± 0.84 | −0.21 ± 0.95 | −0.34 ± 0.87 | 0.82 ± 0.98 |
p = 0.01 | p = 0.01 | p = 0.04 | p = 0.07 | p > 0.2 | p < 0.01 | p > 0.2 | |
GVHD | |||||||
Yes | −1.53 ± 1.10 | −1.24 ± 1.51 | −0.90 ± 2.35 | −0.67 ± 1.36 | −0.17 ± 1.06 | −1.32 ± 1.48 | 0.69 ± 1.28 |
No | −0.67 ± 1.11 | −0.88 ± 1.11 | −0.51 ± 1.10 | −0.47 ± 0.99 | −0.18 ± 1.08 | −0.78 ± 1.19 | 0.91 ± 0.97 |
p < 0.01 | p > 0.2 | p > 0.2 | p > 0.2 | p > 0.2 | p > 0.2 | p > 0.2 | |
GHD | |||||||
Yes | −2.02 ± 0.97 | −1.56 ± 1.62 | −1.64 ± 2.47 | −1.15 ± 1.35 | −0.57 ± 1.19 | −1.69 ± 1.84 | 0.24 ± 1.27 |
No | −0.69 ± 1.04 | −0.84 ± 1.12 | −0.28 ± 1.24 | −0.30 ± 1.00 | 0.00 ± 0.95 | −0.78 ± 1.01 | 1.03 ± 0.99 |
p < 0.001 | p = 0.07 | p = 0.05 | p = 0.03 | p = 0.10 | p = 0.09 | p = 0.04 |
vBMD, volumetric bone mineral density; TBI, total body irradiation; GVHD, graft vs. host disease; GHD, growth hormone deficiency
Cortical vBMD Z-scores did not differ according to treatment and disease characteristics.