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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Mol Pharm. 2015 May 4;12(6):2101–2111. doi: 10.1021/acs.molpharmaceut.5b00071

Figure 4. Analysis of endocytic mechanism for anti-CD19Ab conjugated NPs.

Figure 4

(A) Inhibiting clathrin-mediated uptake of CD19-NR-NPs (final concentration ≈1μM of encapsulated DOX) in RS4;11 cells for 30 min at 37°C. Scale bar, 10 μm. (B) Colocalization of FITC-transferrin and CD19-NR-NPs in RS4;11 cells. Scale bar, 10 μm.