Table 2. Micro-CT analysis and mechanical testing of intact femurs from Sham and OVx mice at 6 weeks post ovary surgery.
| Parameters | Sham | OVx |
|---|---|---|
| Micro-CT analysis of distal femur | ||
| BV/TV (%) | 3.80±0.29 | 1.91±0.21*** |
| Tb.Th (mm) | 0.06±.002 | 0.04±0.005** |
| Tb.N (m/m) | 2.28±0.14 | 1.17±0.16*** |
| Tb.Sp. (mm) | 0.39±0.012 | 0.58±0.02*** |
| SMI | 1.63±0.04 | 2.42±0.10*** |
| Conn.Dn (1/mm3) | 70.32±3.35 | 36.13±3.43*** |
| Micro-CT analysis of femoral shaft | ||
| BV/TV (%) | 52.36±0.51 | 47.92±1.28* |
| T.Ar (mm2) | 1.76±0.04 | 1.64±0.12* |
| Cs.Th (mm) | 0.24±0.0 | 0.18±0.01 * |
| B.Ar (mm2) | 0.86±0.02 | 0.70±0.06* |
| B.Pm (mm) | 8.79±0.25 | 7.27±0.40** |
| Mechanical testing of femoral shaft | ||
| Maximum power (N) | 32.16±2.89 | 20.66±4.07* |
| Energy (mJ) | 5.76±0.68 | 3.11±0.30* |
| Stiffness (N/mm) | 58.51±2.26 | 45.76±3.11** |
N=6
*P<0.05, **P<0.01, ***P<0.001 for significant difference between the Sham and OVx groups