Table 1.
Baseline Characteristics of Paroxysmal versus Persistent Atrial Fibrillation Patients with a Moderate to High Risk of Stroke (CHADS2 Score ≥2)
| Characteristic | Paroxysmal Atrial Fibrillation (N=56,513) |
Persistent Atrial Fibrillation (N=15,459) |
p Value |
|---|---|---|---|
| Patient demographic characteristics | |||
| Age, years | 75.0 ± 11.4 | 76.9 ± 10.8 | <0.001 |
| Male sex | 51.4% | 55.0% | <0.001 |
| Race | <0.001 | ||
| White | 93.6% | 91.9% | |
| Black | 5.0% | 7.1% | |
| Other | 1.5% | 1.1% | |
| Hispanic ethnicity | 5.9% | 3.5% | <0.001 |
| Insurance | <0.001 | ||
| Private | 54.6% | 46.4% | |
| Medicare | 38.0% | 49.8% | |
| Medicaid | 1.0% | 0.8% | |
| Other | 0.6% | 0.3% | |
| Uninsured | 5.8% | 2.6% | |
| Region | <0.001 | ||
| Northeast | 14.0% | 5.5% | |
| Midwest | 32.2% | 51.8% | |
| South | 32.3% | 27.7% | |
| West | 21.4% | 15.0% | |
| Body mass index | 29.2 ± 6.7 | 29.2 ± 6.7 | 0.980 |
| Comorbidities | |||
| CHADS2 Score | 2.9 ± 1.0 | 2.7 ± 0.9 | <0.001 |
| Congestive heart failure | 38.8% | 50.9% | <0.001 |
| Hypertension | 93.2% | 93.1% | 0.693 |
| Diabetes | 34.1% | 30.4% | <0.001 |
| Prior stroke/TIA | 31.9% | 15.8% | <0.001 |
| Systemic embolism | 1.7% | 1.4% | 0.014 |
| Coronary artery disease | 65.5% | 59.2% | <0.001 |
| Prior myocardial infarction | 31.0% | 23.8% | <0.001 |
| Recent CABG or PCI | 23.9% | 13.4% | <0.001 |
| Stable angina | 8.4% | 7.7% | 0.013 |
| Peripheral arterial disease | 15.8% | 12.2% | <0.001 |
| Dyslipidemia | 65.1% | 66.0% | 0.051 |
| Tobacco use | <0.0001 | ||
| Never | 32.8% | 47.4% | |
| Current | 15.0% | 10.7% | |
| Quit within 12 months | 2.6% | 1.4% | |
| Quit more than 12 months ago | 49.6% | 40.5% |
Categorical data are reported as percentages. Continuous data are reported as mean ± SD.
CABG = coronary artery bypass grafting; PCI = percutaneous coronary intervention; TIA = transient ischemic attack.