Table 2. Comparison of the estimates for the effect of first HAART regimen and history of injection drug use on the probability of achieving viral suppression at 6 months according to different methods to control for confounding.
Odds ratio (95% confidence interval) |
||
---|---|---|
No history of injection drug use | History of injection drug use | |
Crude model | ||
First HAART regimen (ATA/r vs. EFV) | 1.66 (1.18–2.33) | 1.51 (1.03–2.23) |
Different modeling techniques | ||
First HAART regimen (ATA/r vs. EFV) | ||
Multivariable model | 1.51 (1.04–2.18) | 1.95 (1.25–3.04) |
Confounder model | 1.51 (1.05–2.17) | 1.95 (1.27–2.98) |
Regression adjusted using propensity score | 1.45 (1.01 –2.07) | 1.76 (1.17–2.63) |
Regression adjusted using quintiles of the propensity score | 1.43 (1.00–2.04) | 1.77 (1.18–2.66) |
Regression adjusted using IPTW | 1.46 (1.15–1.86) | 1.74 (1.32–2.28) |
ATA/r, atazanavir boosted with 400 mg/day or less of ritonavir; EFV, efavirenz; IPTW, inverse probability of treatment weighted.