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. Author manuscript; available in PMC: 2015 Aug 18.
Published in final edited form as: AIDS. 2012 Jul 31;26(12):1491–1500. doi: 10.1097/QAD.0b013e3283550b68

Table 3. Patient characteristics (a) and their influence (b) in explaining the achievement of suppression at 6 months (through separate univariable logistic regressions).

(a)
No history of injection drug use
History of injection drug use
Achieved suppression at 6 months since HAART initiation P value

Factors No (N = 188) Yes (N = 542) No (N = 179) Yes (N = 254)
Sex
Male 163 (17%) 487 (51%) 129 (13%) 186 (19%) <0.0001
Female 25 (13%) 55 (28%) 50 (25%) 68 (34%)
HAART regimen
EFV-based 70 (13%) 269 (49%) 76 (14%) 134 (24%) 0.0035
ATA/r-based 118 (19%) 273 (44%) 103 (17%) 120 (20%)
First year adherence to HAART
>95% 134 (15%) 470 (54%) 77 (9%) 197 (22%) <0.0001
<95% 54 (19%) 72 (25%) 102 (36%) 57 (20%)
First year of HAART
2000–2004 26 (13%) 83 (41%) 39 (19%) 54 (27%) 0.0022
2005–2006 58 (16%) 162 (44%) 65 (17%) 86 (23%)
2007–2009 104 (18%) 297 (50%) 75 (13%) 114 (19%)
Age (years) 44 (38–52) 43 (36–51) 42 (35–48) 43 (37–49) 0.0805
Baseline CD4 cell count (cells/μl) 180 (80–260) 215 (130–280) 150 (90–220) 185 (120–240) <0.0001
Baseline viral load (log10 copies/ml) 5.0 (4.9–5.0) 4.9 (4.4–5.0) 5.0 (4.7–5.0) 4.9 (4.3–5.0) <0.0001
(b)
Influence of each Factor on the achievement of suppression at 6 months since HAART
initiation – AUC (rank)
Factors Overall No history of IDU History of IDU
History of injection drug use 0.584 (4) NA NA
Sex 0.525 (6) 0.516 (6) 0.506 (7)
HAART regimen 0.554 (5) 0.562 (4) 0.551 (4)
First year adherence to HAART 0.632 (1) 0.577 (3) 0.673 (1)
First year of HAART 0.516 (7) 0.509 (7) 0.517 (6)
Age (years) 0.504 (8) 0.534 (5) 0.537 (5)
Baseline CD4 cell count (cells/μl) 0.592 (3) 0.585 (2) 0.583 (3)
Baseline viral load (log10 copies/ml) 0.627 (2) 0.662 (1) 0.592 (2)

ATA/r, atazanavir boosted with 400 mg/day or less of ritonavir; AUC, area under the receiver operating curve; EFV, efavirenz.