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. 2015 Aug 18;11(8):e1005102. doi: 10.1371/journal.ppat.1005102

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Fig 6 — Tax interacts with and stimulates RNF8 and Ubc13:Uev1A/2 to assemble free K63-pUb chains, which serve as platforms for TAK1 and IKK to convene and activate the canonical NF-κB and other signaling pathways.