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. 2015 Aug 18;10(8):e0135892. doi: 10.1371/journal.pone.0135892

Fig 3. Mechanosensitivity of gastric vagal afferent tension receptors in the absence and presence of N-oleoyldopamine (OLDA).

Fig 3

(A) In mice fed a SLD (N = 6), the response of gastric tension receptors to 3 g circular stretch. * p<0.05 vs. 0μM OLDA. (B) Typical response of a gastric tension receptor from a SLD mouse to 3 g tension in the (i) absence and (ii) presence of the TRPV1 agonist OLDA (10μM). (C) In mice fed a HFD (N = 6), the response of gastric tension receptors to 3 g circular stretch. (D) Percentage potentiation, in the presence of OLDA (0.1–10 μM), of gastric tension receptor responses to 3 g circular stretch in mice fed a SLD (■; N = 6) or a HFD (●: N = 6). ***p<0.001; diet effect, two-way ANOVA.