Fig 3. IL-22 regulates the expression of skin repair genes during L. major infection.

(A-B) Wild-type and Il22 ^-/- mice were intradermally infected with 2 x10⁶ L. major promastigote metacyclics and RNA was isolated from the lesions at 5 weeks post-infection to assess gene expression. Data are represented as relative expression to housekeeping gene rps11 and are representative of at least 2 independent experiments, with 3–5 mice per group. Error bars indicate mean ± SEM, *p < 0.05.