Table 2. Physiological characteristics of mice by group.
| Endpoint | Wt | LF | HF | DbDb | 2Way ANOVA P | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| M (7) | F (5) | M (4) | F (5) | M (4) | F (8) | M (3) | F (7) | Group | Sex | |
| Body weight (g) | 31.31±2.33 | 23.58±1.42 | 30.83±1.80 | 22.60±0.46 | 44.41±3.66* | 29.73±1.83 | 51.13±1.38* | 49.17±3.51* | <0.0001 | <0.0001 |
| Total fat mass (g) | 8.05±1.70 | 5.07±0.89 | 7.60±1.41 | 4.85±1.04 | 19.13±3.08* | 9.94±1.96 | 28.22±1.04* | 26.51±1.93* | <0.0001 | 0.006 |
| Total lean mass (g) | 18.95±0.85 | 15.24±0.86 | 18.66±0.32 | 14.27±1.14 | 21.06±1.17 | 16.75±0.37 | 18.89±0.62 | 17.39±1.56 | 0.1 | <0.0001 |
| Mesenteric fat (g) | 0.55±0.11 | 0.28±0.07 | 0.41±0.07 | 0.28±0.04 | 1.23±0.28* | 0.39±0.09 | 1.04±0.16 | 1.00±0.13* | <0.0001 | 0.002 |
| Gonadal fat (g) | 1.01±0.24 | 0.58±0.15 | 0.97±0.18 | 0.52±0.09 | 2.48±0.26* | 1.53±0.35 | 1.57±0.18 | 1.84±0.26* | <0.0001 | 0.063 |
| Liver (g) | 1.29±0.17 | 0.94±0.10 | 1.19±0.06 | 1.04±0.07 | 1.33±0.15 | 0.96±0.04 | 4.93±0.30* | 3.63±0.29* | <0.0001 | <0.0001 |
| Plasma insulin (ng/ml) | 3.10±1.26 | 0.94±0.16 | 1.70±0.23 | 1.20±0.20 | 4.09±1.91 | 1.09±0.18 | 11.44±0.82 | 16.03±2.43* | <0.0001 | 0.8 |
| Plasma glucose (μM) | 8.09±0.87 | 5.08±2.56 | 8.21±0.42 | 7.78±0.47 | 11.19±1.07 | 10.05±0.92 | 20.81±1.73* | 18.26±2.51* | <0.0001 | 0.1 |
Total lean and fat mass measured by MRI. M, male; F, female. Samples size in parentheses.
* p<0.05 vs LF (of same sex).