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. 2015 Aug 18;10(8):e0134212. doi: 10.1371/journal.pone.0134212

Fig 4. Deletion of epithelial Dclk1 exacerbates DSS-induced inflammation of the colonic mucosa.

Fig 4

A. Colonic MPO activity was dramatically increased in the VillinCre;Dclk1f/f mice following DSS treatment; B. The mRNA expression levels of Ptgs2, Il6, Il1β, Cxcl1, and Cxcl2 in colonic tissues were measured by quantitative real-time RT-PCR, and normalized against β-actin. Values in the bar graphs are given as mean ± SEM, *p<0.02, **** p<0.0001 VillinCre;Dclk1f/f vs Dclk1f/f; C. The protein expression level of RelA in colonic tissues was analyzed by Western blotting.