Fig 7. Dclk1 epithelial deletion increases disease activity following DSS-induced colitis.
Both VillinCre;Dclk1f/f and Dclk1f/f mice were fed with 3% DSS in drinking water for 9 days followed by regular drinking water for 2 days to induce colitis (n = 8 for each group). A. Body weight. B. Diarrhea score. C. Fecal blood score. D. Disease activity index. E. Kaplan-Meier survival curve (dashed line = VillinCre;Dclk1f/f, solid line = Dclk1f/f). Data are presented as the mean ± S.E.M. *p<0.05 VillinCre;Dclk1f/f vs Dclk1f/f.