Table 3. Comparison of efficacy between combined therapy and chemotherapy or EGFR TKIs alone.

	Heterogeneity		HR/RR	Begg's test		Egger's test
	P value	I 2	(95%CI)	Z	P	t	P
Synchronous combined group vs. chemotherapy group
OS	0.953	0.00	1.05(0.98–1.12)	0.90	0.368	-0.48	0.653
PFS	NE	NE	0.77(0.51–1.17)	NE	NE	NE	NE
TTP	0.920	0.00	0.94(0.89–1.00)	0.75	0.452	-0.91	0.413
ORR	0.475	0.00	1.07(0.98–1.17)	1.22	0.221	2.46	0.091
Synchronous combined group vs. EGFR TKIs group
OS	0.679	0.00	1.10(0.83–1.46)	NE	NE	NE	NE
PFS	0.721	0.00	0.86(0.67–1.10)	NE	NE	NE	NE