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. Author manuscript; available in PMC: 2015 Aug 18.
Published in final edited form as: FEBS J. 2012 Jan 13;279(4):650–660. doi: 10.1111/j.1742-4658.2011.08459.x

Fig. 2.

Fig. 2

cAMP accumulation in response to Isoproterenol. S49 cyc– cells transfected with Gαs-wt were exposed to different doses of isoproterenol for 45 min (acute) and 24 h (chronic), and then the cAMP concentration was assayed with a competitive ELISA method (A; n = 5). The effects of (B) acute and (C) chronic isoproterenol (10 μM) on the cAMP concentration were studied in cyc– cells transfected with indicated constructs. The data are presented as the ratio to control. *Compared to cyc–; mean ± SD; n = 7.